New targets found to reduce blood vessel damage in diabetes
Levels of the enzyme PDIA1, which enables a healthy homeostasis of endothelial cells as well as production of new blood vessels, decrease in diabetes, while activity of Drp1, a key regulator of fission regulated by PDIA1, goes way up, a new study finds.
Original source: https://www.sciencedaily.com/releases/2018/07/180709101158.htm